Abstract

From molecules, single cells and tissues to whole organisms, our insights into Ca²⁺ signalling and the corresponding physiological phenomena are growing exponentially. Here, we describe the improvements that have been made in the development of the probes and instrumentation that are used for Ca²⁺ imaging and the expanding applications of Ca²⁺ imaging in basic and applied research.

Author affiliations

1. Rüdiger Rudolf and Tullio Pozzan are at the Department of Biomedical Sciences, CNR Institute of Neurosciences, University of Padova, via G. Columbo 3, 35121 Padova, Italy.
2. Marco Mongillo and Tullio Pozzan are at the Venetian Institute for Molecular Medicine, via Orus 2, 35129 Padova, Italy.
3. Rosario Rizzuto is at the Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, via Borsari 46, 44100 Ferrara, Italy.

Correspondence to: Tullio Pozzan^1,2 Email: tullio.pozzan@unipd.it