Perspectives

Nature Reviews Molecular Cell Biology 4, 580-585 (July 2003) | doi:10.1038/nrm1152

Timeline20 years of Ins(1,4,5)P3, and 40 years before

Robin F. Irvine1  About the author

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This year marks the 20th birthday of the discovery of inositol-1,4,5-trisphosphate as a second messenger. The background to this discovery is a complex story that goes back more than 50 years and involves a large cast of characters, both chemical and human.

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Author affiliations

  1. Robin F. Irvine is at the Department of Pharmacology, Tennis Court Road, Cambridge CB2 1QJ, UK.
    Email: rfi20@cam.ac.uk
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