Review

Nature Reviews Molecular Cell Biology 4, 349-361 (May 2003) | doi:10.1038/nrm1100

Nuclear lipid signalling

Robin F. Irvine1  About the author

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During the past twenty years, evidence has accumulated for the presence of phospholipids within the nuclei of eukaryotic cells. These phospholipids are distinct from those that are obviously present in the nuclear envelope. The best characterized of the intranuclear lipids are the inositol lipids that form the components of a phosphoinositide–phospholipase C cycle. However, exactly as has been discovered in the cytoplasm, this is just part of a complex picture that involves many other lipids and functions.

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Author affiliations

  1. Department of Pharmacology, Tennis Court Road, Cambridge CB2 1QJ, UK.
    Email: rfi20@cam.ac.uk
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REFERENCE
Glycerophospholipids
Nature Encyclopaedia of Life Sciences

NEWS AND VIEWS
Signal transduction: Inositol lipid pathways turn turtle
Nature News and Views (13 Nov 1997)
Vesicular transport: Sticky fingers grab a lipid
Nature News and Views (30 Jul 1998)
See all 3 matches for News And Views

RESEARCH
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1
Nature Cell Biology Article (01 Apr 2003)

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