Review
Nature Reviews Molecular Cell Biology 4, 225-237 (March 2003) | doi:10.1038/nrm1055
Signalling to and from tight junctions
Karl Matter1 & Maria S. Balda1 About the authors
Abstract
Tight junctions have long been regarded as simple barriers that separate compartments of different compositions, but recent research indicates that different types of signalling proteins and transduction pathways are associated with these junctions. They receive and convert signals from the cell interior to regulate junction assembly and function, and transmit signals to the cell interior to modulate gene expression and cell behaviour.
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Author affiliations
- Division of Cell Biology, Institute of Ophthalmology, University College London, London, UK.
Correspondence to: Karl Matter1 Email: k.matter@ucl.ac.uk
Correspondence to: Maria S. Balda1 Email: m.balda@ucl.ac.uk
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