Review
Nature Reviews Molecular Cell Biology 4, 798-807 (October 2003) | doi:10.1038/nrm1224
Cell-death alternative model organisms: why and which?
Pierre Golstein1, Laurence Aubry2 & Jean-Pierre Levraud3 About the authors
Abstract
Classical model organisms have helped greatly in our understanding of cell death but, at the same time, might have constrained it. The use of other, non-classical model organisms from all biological kingdoms could reveal undetected molecular pathways and better-defined morphological types of cell death. Here we discuss what is known and what might be learned from these alternative model systems.
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Author affiliations
- Pierre Golstein, Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM-l'Université de la Mediteranée, Parc Scientifique de Luminy, Case 906, 13288 Marseille cedex 9, France.
- Laurence Aubry, CEA-Grenoble, 17 rue des Martyrs, 38054 Grenoble cedex 09, France.
- Jean-Pierre Levraud, Unité Macrophages et Développement de l'Immunité, Institut Pasteur, 25, rue du Dr Roux, 75724 Paris cedex 15, France.
Correspondence to: Pierre Golstein1 Email: golstein@ciml.univ-mrs.fr
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