Review

Nature Reviews Molecular Cell Biology 3, 685-695 (September 2002) | doi:10.1038/nrm907

Listening in on bacteria: acyl-homoserine lactone signalling

Clay Fuqua1 & E. Peter Greenberg2  About the authors

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Bacterial cell-to-cell signalling has emerged as a new area in microbiology. Individual bacterial cells communicate with each other and co-ordinate group activities. Although a lot of detail is known about the mechanisms of a few well-characterized bacterial communication systems, other systems have been discovered only recently. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs.

Author affiliations

  1. Department of Biology, Indiana University, Jordan Hall 142, 1001 East 3rd Street, Bloomington, Indiana 47405, USA.
  2. Department of Microbiology, University of Iowa, Iowa City, Iowa 52242, USA.

Correspondence to: E. Peter Greenberg2 Email: everett-greenberg@uiowa.edu

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REFERENCE
Quorum Sensing
Nature Encyclopaedia of Life Sciences

NEWS AND VIEWS
Plant microbiology: Quieting the raucous crowd
Nature News and Views (14 Jun 2001)

RESEARCH
Quorum-sensing signal binding results in dimerization of TraR and its release from membranes into the cytoplasm
The EMBO Journal Article (02 Oct 2000)
N-acyl homoserine lactone binding to the CarR receptor determines quorum-sensing specificity in Erwinia
The EMBO Journal Article (15 Feb 2000)
The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA
The EMBO Journal Article (02 Sep 2002)
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