Review
Nature Reviews Molecular Cell Biology 3, 919-931 (December 2002) | doi:10.1038/nrm974
There is a Correction (1 February 2003) associated with this article.
Sorting out the cellular functions of sorting nexins
Carolyn A. Worby1 & Jack E. Dixon1 About the authors
Abstract
Sorting nexins are a diverse group of cellular trafficking proteins that are unified by the presence of a phospholipid-binding motif — the PX domain. The ability of these proteins to bind specific phospholipids, as well as their propensity to form protein–protein complexes, points to a role for these proteins in membrane trafficking and protein sorting. It will be interesting to determine whether the various sorting nexins have specialized or generalized roles in protein trafficking.
- View At a Glance
Author affiliations
- Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.
Correspondence to: Carolyn A. Worby1 Email: cdworby@umich.edu
|
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated NEWS AND VIEWS RESEARCH |
