Review

Nature Reviews Molecular Cell Biology 2, 350-356 (May 2001) | doi:10.1038/35073038

Protein targeting by the twin-arginine translocation pathway

Colin Robinson1 & Albert Bolhuis1  About the authors

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The twin-arginine translocation pathway operates in the thylakoid membrane of chloroplasts and in the plasma membrane of most free-living bacteria. Its main function is to transport fully folded proteins across the membrane. Three important tat genes have been identified and the sequences of the encoded proteins, together with the unusual properties of the pathway, indicate that the Tat system is completely different from other protein translocases.

Author affiliations

  1. Department of Biological Sciences, University of Warwick , Coventry CV4 7AL, United Kingdom. Email:  crobinson@bio.warwick.ac.uk

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