Review
Nature Reviews Molecular Cell Biology 2, 908-916 (December 2001) | doi:10.1038/35103078
Milestones: Network dynamics and cell physiology
John J. Tyson1, Kathy Chen1 & Bela Novak2 About the authors
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Abstract
Complex assemblies of interacting proteins carry out most of the interesting jobs in a cell, such as metabolism, DNA synthesis, movement and information processing. These physiological properties play out as a subtle molecular dance, choreographed by underlying regulatory networks. To understand this dance, a new breed of theoretical molecular biologists reproduces these networks in computers and in the mathematical language of dynamical systems.
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Author affiliations
- Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.
- Department of Agricultural Chemical Technology, Budapest University of Technology and Economics, Budapest 1521, Hungary.
Correspondence to: John J. Tyson1 Email: tyson@vt.edu, Email: kchen@vt.edu, Email: bnovak@chem.bme.hu
