Review

Nature Reviews Molecular Cell Biology 2, 815-826 (November 2001) | doi:10.1038/35099020

MEN and SIN: what's the difference?

Allison J. Bardin1 & Angelika Amon1  About the authors

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A conserved signalling cascade — termed the mitotic-exit network in budding yeast and the septation-initiation network in fission yeast — controls key events during exit from mitosis and cytokinesis. Although the components of these signalling networks are highly conserved between the two yeasts, the outputs seem quite different. How, then, do these two pathways function, and how are they regulated?

Author affiliations

  1. Center for Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, E17-233, 40 Ames Street, Cambridge, Massachusetts 02139, USA.

Correspondence to: Angelika Amon1 Email: angelika@mit.edu

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