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Nature Reviews Molecular Cell Biology 2, 769–776 (1 October 2001) | doi:10.1038/35096075
The renaissance of GSK3
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Abstract
Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.
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