Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Review
Nature Reviews Molecular Cell Biology 1, 22–30 (1 October 2000) | doi:10.1038/35036044
A tale of toroids in DNA metabolism
&
Abstract
A strikingly large number of the proteins involved in DNA metabolism adopt a toroidal ? or ring-shaped ? quaternary structure, even though they have completely unrelated functions. Given that these proteins all use DNA as a substrate, their convergence to one shape is probably not a coincidence. Ring-forming proteins may have been selected during evolution for advantages conferred by the toroidal shape on their interactions with DNA.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
