Dendritic cells: controllers of adaptive immunity

Miriam Merad

Dendritic cells (DCs) are a heterogenous population of antigen-presenting cells that have crucial roles in promoting both pro- and anti-inflammatory immune responses. They monitor the body's tissues and can integrate multiple signals from the environment in order to initiate an appropriate adaptive immune response. Inflammatory signals promote DC activation and their migration to draining lymphoid tissues to prime effector T cell responses. However, in the steady state, DCs promote tissue homeostasis by supporting the induction of regulatory T cells.

This Poster provides an overview of some of the key ways in which DCs contribute to adaptive immunity.

The Poster is freely available thanks to support from BioLegend.