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Nature Reviews Immunology 9, 458 (1 July 2009) | doi:10.1038/nri2593

T cell memory: Keeping energy levels up

Lucy Bird

A recent study published in Nature suggests that the generation of a long-lived memory CD8+ T cell population depends on a switch in energy metabolism from glucose to fatty acid metabolism. Modulation of this metabolic transition shows promise as an approach to boost vaccine efficacy.