Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Research Highlights
Nature Reviews Immunology 8, 905 (1 December 2008) | doi:10.1038/nri2463
T-cell memory: Growing with experience
Abstract
The generation of memory CD8+ T cells following exposure to a pathogen or vaccine is required for protection against subsequent infections by the same pathogen. It has long been thought that the maximum size of the memory CD8+ T-cell compartment is fixed and, consequently, that the generation of memory CD8+ T cells of new specificities must necessarily reduce the number of pre-existing memory CD8+ T cells.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
