Figures and Tables

From the following article:

Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

Pärt Peterson, Tõnis Org & Ana Rebane

Nature Reviews Immunology 8, 948-957 (December 2008)

doi:10.1038/nri2450

Figure 1 - Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

Figure 1

Schematic representation of the human AIRE protein.

Figure 2 - Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

Figure 2

Proposed mechanism of AIRE-mediated gene activation.

Figure 3 - Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

Figure 3

Stochastic and coordinated regulation of target genes.