Figures and Tables
From the following article:
Calcium signalling in lymphocyte activation and disease
Stefan Feske
Nature Reviews Immunology 7, 690-702 (September 2007)
doi:10.1038/nri2152
Figure 1
Store-operated calcium entry (SOCE) in T cells.
Figure 2
Domain architecture of the CRAC channel subunit ORAI1 and the Ca2+ sensor in the endoplasmic reticulum STIM1.
Figure 3
Redistribution of STIM1 following Ca2+ store depletion.
Figure 4
Mechanisms regulating Ca2+ levels in T cells.
Figure 5
The CRAC-channel–calcium–calcineurin–NFAT signalling pathway as a target for therapeutic immune modulation.
Table 1
Ca2+ signalling pathways and functions in cells of the immune system*
