Figures and Tables
From the following article:
Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network
Hugh Rosen & Edward J. Goetzl
Nature Reviews Immunology 5, 560-570 (July 2005)
doi:10.1038/nri1650
Figure 1
Sources of lysophospholipids in the immune system.
Figure 2
S1P1 pathways of intracellular trafficking and signalling.
Figure 3
Effects of S1P1 signalling on lymphocyte trafficking and tissue distribution.
Figure 4
S1P–S1P-receptor systems in the regulation of IgE production and mast-cell activation.
Figure 5
Postulated contributions of lymphocytes and endothelial cells to control of lymphocyte trafficking by the S1P–S1P1 system.
Table 1
S1P receptors and their effects on immune cells
