Review
Nature Reviews Immunology 2, 239-250 (April 2002) | doi:10.1038/nri776
Subject Category: Vaccines
Vaccines: New hope for an aids vaccine
Harriet L. Robinson1 About the author
Abstract
The twenty-first century has begun with considerable success for new AIDS vaccines in macaque models. A common feature of these vaccines is their ability to induce high-frequency CD8+ T-cell responses that control, rather than prevent, infection with HIV. The new vaccines, which include DNA vaccines and live viral vectors, are based on technologies that have been developed since the start of the AIDS epidemic. The ultimate promise of these vaccines will be realized only when efficacy trials in humans are conducted.
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Author affiliations
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Vaccine Research Center and Yerkes Primate Research Center of Emory University, 954 Gatewood Drive, NE, Atlanta, Georgia 30329, USA
Email: hrobins@rmy.emory.edu
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