Review
Nature Reviews Immunology 2, 77-84 (February 2002) | doi:10.1038/nri723
There is an Erratum (1 May 2002) associated with this article.
C-type lectin receptors on dendritic cells and langerhans cells
Carl G. Figdor1, Yvette van Kooyk2 & Gosse J. Adema1 About the authors
Abstract
Dendritic cells and Langerhans cells are specialized for the recognition of pathogens and have a pivotal role in the control of immunity. As guardians of the immune system, they are present in essentially every organ and tissue, where they operate at the interface of innate and acquired immunity. Recently, several C-type lectin and lectin-like receptors have been characterized that are expressed abundantly on the surface of these professional antigen-presenting cells. It is now becoming clear that lectin receptors not only serve as antigen receptors but also regulate the migration of dendritic cells and their interaction with lymphocytes.
- View At a Glance
Author affiliations
- Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, NCMLS/187 Til, Postbox 9101, 6500HB Nijmegen, The Netherlands.
- Department of Molecular Cell Biology, Free University Medical Centre, Amsterdam.
Correspondence to: Carl G. Figdor1 Email: c.figdor@mailbox.kun.nl
|
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated NEWS AND VIEWS |
