Nature Reviews Immunology 12, 237 (April 2012) | doi:10.1038/nri3197

Focus on: Tumour immunology & immunotherapy

Tumour immunotherapy — leukocytes take up the fight

Gemma K. Alderton1 & Yvonne Bordon2


The immune system can promote the elimination of tumours, but often immune responses are modulated or suppressed by the tumour microenvironment. In this joint Focus from Nature Reviews Cancer and Nature Reviews Immunology, leading researchers describe our current understanding of the complex interactions that occur between the immune system and tumour cells, and discuss how the power of the immune system can be harnessed by anticancer immunotherapies.

Author affiliations

  1. Gemma K. Alderton, Senior Editor, Nature Reviews Cancer
  2. Yvonne Bordon, Associate Editor, Nature Reviews Immunology

Published online 22 March 2012