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A collection of articles from the Nature Publishing Group. Select the
links below for full-text access.
Innate immunity is the first line of defence against pathogens and is
initiated rapidly after recognition of microbial products by receptors
such as the Toll-like receptors (TLRs). Identifying the TLRs, their ligands
and the signal transduction events that they initiate has provided insight
into our understanding of how the immune response to infection begins,
as highlighted in our Foreword.
This Web Focus on TLR signalling accompanies the July 2004 issue of
Nature Reviews Immunology and with the support of 3M
Pharmaceuticals is available free online for three months (July-September).
Included are articles from Nature Reviews Immunology that outline
the signalling cascades initiated by TLR triggering and the therapeutic
potential of targeting this pathway, as well as relevant Highlight articles
from the journal. The TLR-signalling pathway is also illustrated in a
poster that will be updated online every three months to incorporate the
rapidly emerging new data. To complete the collection, we have added relevant
papers published in the last year by other journals of the Nature Publishing
Group.
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