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Viewpoints


It seems there are more questions than answers on the topic of regulatory T cells. How many different subsets are there? How do they work? What is their therapeutic potential?
Find out what some of the experts in immune regulation think in this special collection of personal perspectives.

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CD4+CD25+ TReg cells
– the renaissance of suppressor T cells?

Alexander H. Enk
Regulatory CD4+CD25+ T cells are 'suppressor' T cells
Joerg Ermann & C. Garrison Fathman
Do CD4+CD25+ T cells explain the specificity of dominant tolerance?
Herman Waldmann and Luis Graca
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T-cell regulation without regulatory T cells
Brigitta Stockinger, Thomas Barthlott & George Kassiotis
CD4+CD25+ TReg cells: naturally occurring but adaptable
Ciriaco A. Piccirillo & Ethan M. Shevach
TReg cells and allergy: a question of balance and antigen specificity
Mübeccel Akdis, Kurt Blaser & Cezmi A. Akdis
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TReg cells and
'strength-of-signal'-based strategies

Av Mitchison
Looking beyond the current dogma
William R. Heath & Francis R. Carbone

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