NPG Library
Below is a selection of recent Research Highlights, News and Views, Review Articles and Essays that have been published by Nature Publishing Group journals on the topic of allergy and asthma.
Research Highlights
Signalling: The ins and outs of Ca2+ signalling in mast cells
Elaine Bell
doi:10.1038/nri2245
Nature Reviews Immunology 8, 6-7 (2008)
Allergy and Asthma: Opposing roles for osteopontin
Lucy Bird
doi:10.1038/nri2109
Nature Reviews Immunology 7, 417 (2007)
News and Views
Do antihistamines make allergies worse?
Matt Kaplan
doi:10.1038/news.2008.436
Nature News(2007)
Caesarian sections may increase asthma risk
Matt Kaplan
doi:10.1038/news.2007.201
Nature News (2007)
The bridge between dendritic cells and asthma
Mari L Shinohara & Harvey Cantor
doi:10.1038/nm0507-536
Nature Medicine 13, 536-538 (2007)
Reviews and Essay
Regulation of immunological homeostasis in the respiratory tract
Patrick G. Holt, Deborah H. Strickland, Matthew E. Wikström & Frode L. Jahnsen
doi:10.1038/nri2236
Nature Reviews Immunology 8, 142-152 (2008)
The cysteinyl leukotrienes: Where do they come from? What are they? Where are they going?
K Frank Austen
doi:10.1038/ni0208-113
Nature Immunology 9, 113-115 (2008)
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines
Robin L. Thurmond, Erwin W. Gelfand & Paul J. Dunford
doi:10.1038/nrd2465
Nature Reviews Drug Discovery 7, 41-53 (2008)
The evolution of clinical immunology and allergy in Australia
Antony Basten
doi:10.1038/sj.icb.7100138
Immunology and Cell Biology 86, 16-21 (2008)
The contribution of toll-like receptors to the pathogenesis of asthma
Simon Phipps, Chuan En Lam, Paul S Foster & Klaus I Matthaei
doi:10.1038/sj.icb.7100104
Immunology and Cell Biology 85, 463-470 (2007)
The regulatory role of TGF-
in airway remodeling in asthma
Toluwalope Makinde, Richard F Murphy & Devendra K Agrawal
doi:10.1038/sj.icb.7100044
Immunology and Cell Biology 85, 348-356 (2007)
Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
Roy Pettipher, Trevor T. Hansel & Richard Armer
doi:10.1038/nrd2266
Nature Reviews Drug Discovery 6, 313-325 (2007)
Role of mast cells in allergic and non-allergic immune responses: comparison of human and murine data
Stephan C. Bischoff
doi:10.1038/nri2018
Nature Reviews Immunology 7, 93-104 (2007)
A role for natural killer T cells in asthma
Dale T. Umetsu & Rosemarie H. DeKruyff
doi:10.1038/nri1968
Nature Reviews Immunology 6, 953-958 (2006)
Immunological mechanisms of allergen-specific immunotherapy
Mark Larché, Cezmi A. Akdis & Rudolf Valenta
doi:10.1038/nri1934
Nature Reviews Immunology 6, 761-771 (2006)
Research articles
Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma
Valérie Verhasselt, Valérie Milcent, Julie Cazareth, Akira Kanda, Sébastien Fleury, David Dombrowicz, Nicolas Glaichenhaus & Valérie Julia
doi:10.1038/nm1718
Nature Medicine 14, 170-175 (2008)
Suppression of immunoglobulin E–mediated allergic responses by regulator of G protein signaling 13
Geetanjali Bansal, Zhihui Xie, Sudhir Rao, Karl H Nocka & Kirk M Druey
doi:10.1038/ni1533
Nature Immunology 9, 73-80 (2008)
A mechanism for the initiation of allergen-induced T helper type 2 responses
Caroline L Sokol, Gregory M Barton, Andrew G Farr & Ruslan Medzhitov
doi:10.1038/ni1558
Nature Immunology 9, 310-318 (2008)
Diesel exhaust particulate matter induces multinucleate cells and zinc transporter-dependent apoptosis in human airway cells
Margaret Leigh Ackland, Linda Zou, David Freestone, Simone van de Waasenburg & Agnes A Michalczyk
doi:10.1038/sj.icb.7100109
Immunology and Cell Biology 85, 617-622 (2007)
Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease
Markus Weckmann, Adam Collison, Jodie L Simpson, Matthias V Kopp, Peter A B Wark, Mark J Smyth, Hideo Yagita, Klaus I Matthaei, Nicole Hansbro, Bruce Whitehead, Peter G Gibson, Paul S Foster & Joerg Mattes
doi:10.1038/nm1660
Nature Medicine 13, 1308-1315 (2007)
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
Miriam F. Moffatt, Michael Kabesch, Liming Liang, Anna L. Dixon, David Strachan, Simon Heath, Martin Depner, Andrea von Berg, Albrecht Bufe, Ernst Rietschel, Andrea Heinzmann, Burkard Simma, Thomas Frischer, Saffron A. G. Willis-Owen, Kenny C. C. Wong, Thomas Illig, Christian Vogelberg, Stephan K. Weiland, Erika von Mutius, Gonçalo R. Abecasis, Martin Farrall, Ivo G. Gut, G. Mark Lathrop & William O. C. Cookson
doi:10.1038/nature06014
Nature 448, 470-473 (2007)
Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets
Georgina Xanthou, Themis Alissafi, Maria Semitekolou, Davina C M Simoes, Erasmia Economidou, Mina Gaga, Bart N Lambrecht, Clare M Lloyd & Vily Panoutsakopoulou
doi:10.1038/nm1580
Nature Medicine 13, 570-578 (2007)
Chitin induces accumulation in tissue of innate immune cells associated with allergy
Tiffany A. Reese, Hong-Erh Liang, Andrew M. Tager, Andrew D. Luster, Nico Van Rooijen, David Voehringer & Richard M. Locksley
doi:10.1038/nature05746
Nature 447, 92-96 (2007)