Top 10
The top ten charts the articles that have been downloaded most often, in HTML format, from the Nature Reviews Gastroenterology & Hepatology website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.
Top of pageNews and Views
Hepatitis: Monitoring drug therapy for hepatitis B—a global challenge?
Tin Nguyen & Stephen Locarnini
doi:10.1038/nrgastro.2009.160
Review
Management of gastric polyps: a pathology-based guide for gastroenterologists
Susanne W. Carmack, Robert M. Genta, David Y. Graham & Gregory Y. Lauwers
doi:10.1038/nrgastro.2009.70
Appropriate clinical and pathological evaluation is crucial for the diagnosis and management of gastric polyps and polypoid lesions. This Review discusses the endoscopic characteristics, histopathology, pathogenesis and management of polyps and common polypoid lesions in the stomach, and provides a practical guide for gastroenterologists.
Case Study
Biliary sludge and acute pancreatitis during pregnancy
Cynthia Ko
doi:10.1038/ncpgasthep0390
Research Highlight
Review
How to critically appraise an article
Jane M Young & Michael J Solomon
doi:10.1038/ncpgasthep1331
To practice evidence-based medicine, clinicians need to apply the findings of scientific research to the circumstances of individual patients as part of the process of clinical decision-making. This Review article presents a 10-step guide to the critical appraisal of research literature to assist clinicians with the task of identifying the most relevant, high-quality studies available to guide their practice.
Review
Pathophysiology, diagnosis and management of postoperative dumping syndrome
Jan Tack, Joris Arts, Philip Caenepeel, Dominiek De Wulf & Raf Bisschops
doi:10.1038/nrgastro.2009.148
The signs and symptoms of dumping syndrome, a well-established complication of gastric and esophageal surgery, result from rapid gastric emptying and the delivery of large particles of poorly digested food to the small bowel. These symptoms, which can be classed as early or late, their pathophysiological basis, and the treatment options available to patients with dumping syndrome are outlined in this article.
Research Highlight
Cancer: Diabetes therapies affect pancreatic cancer risk
Susan J. Allison
doi:10.1038/nrgastro.2009.151
Research Highlight
IBD: Risk of IBD increases after Salmonella or Campylobacter gastroenteritis
Ezzie Hutchinson
doi:10.1038/nrgastro.2009.152
Review
Eosinophilic esophagitis: the newest esophageal inflammatory disease
Dan Atkins, Robert Kramer, Kelley Capocelli, Mark Lovell & Glenn T. Furuta
doi:10.1038/nrgastro.2009.45
Eosinophilic esophagitis is a chronic esophageal inflammatory disease of undetermined pathophysiology resulting in dense mucosal eosinophilia and esophageal dysfunction. This Review discusses the disease in terms of its clinical presentation in children and adults, pathogenesis, diagnosis and treatment.
Review
Surgical management of rectal prolapse
Eric L Marderstein & Conor P Delaney
doi:10.1038/ncpgasthep0952
Rectal prolapse causes significant discomfort because of the sensation of the prolapse itself, the mucus that it secretes, and because it tends to stretch the anal sphincters and cause incontinence. Treatment is primarily surgical; however, there are different opinions about which type of surgical repair is best. The authors of this Review discuss the pathogenesis, clinical presentation, evaluation and surgical management of rectal prolapse.
