Case Study
Nature Reviews Gastroenterology and Hepatology 6, 372-375 (June 2009) | doi:10.1038/nrgastro.2009.65
Subject Categories: Hepatitis | Liver
Treatment of chronic hepatitis C in a slow responder: a case for extended therapy
Paul J. Gaglio1 About the author
Abstract
Background. A 49-year-old white man presented to his primary-care clinic with fatigue and poor concentration. He had an enlarged liver with a minimally tender edge and was subsequently referred to our liver clinic.
Investigations. Physical examination, laboratory investigations (including tests for HCV-RNA, antibodies to hepatitis B surface and core antigens, and HBV-DNA), and liver biopsy.
Diagnosis. The patient had chronic hepatitis C infection and was a slow responder to treatment.
Management. Administration of pegylated interferon 
2b plus ribavirin for 72 weeks. Escitalopram was given to manage his depression.
Author affiliations
- Montefiore-Einstein Liver Center, Greene Medical Arts Pavilion, Bronx, NY, USA.
Correspondence to:
Montefiore-Einstein Liver Center, Greene Medical Arts Pavilion, Suite LL-400, 3400 Bainbridge Avenue, Bronx, NY 10467, USA
Email: pgaglio@montefiore.org
