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Nature Reviews Gastroenterology and Hepatology 6, 129–130 (1 March 2009) | doi:10.1038/ncpgasthep1346
Similar risk of lower gastrointestinal events with etoricoxib and diclofenac
Abstract
Laine L et al. (2008) Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac. Gastroenterology 135: 1517–1525 The association between NSAIDs and upper gastrointestinal events, such as perforation, ulceration and bleeding, is well known.
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