Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

Feasibility of combined EUS–FNA and ERCP for obstructive jaundice from presumed pancreatic malignancy

Abstract

The management of patients with pancreatic cancer begins with confirmation of the diagnosis by cytology, which is followed by accurate preoperative staging and biliary drainage. Endoscopic ultrasonography with fine-needle aspiration (EUS–FNA) followed by endoscopic retrograde cholangiopancreatography (ERCP) helps to achieve these goals and primes the patient for various treatment options. We discuss the findings of a study by Ross and colleagues that aimed to determine the feasibility and outcomes of combining EUS–FNA and therapeutic ERCP in a single session. The authors concluded that combined EUS–FNA and ERCP was technically feasible, and could safely and effectively achieve a diagnosis and biliary drainage. The adverse event rate was acceptable; pancreatitis was the most common complication. Such a one-step approach is, therefore, beneficial and calls for the founding of well-equipped units with adequately skilled endoscopy and support staff.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Rosch T et al. (2004) ERCP or EUS for tissue diagnosis of biliary strictures? A prospective comparative study. Gastrointest Endosc 60: 390–396

    Article  Google Scholar 

  2. Eloubeidi MA et al. (2003) Endoscopic ultrasound-guided fine needle aspiration biopsy of patients with suspected pancreatic cancer: diagnostic accuracy and acute and 30-day complications. Am J Gastroenterol 98: 2663–2668

    PubMed  Google Scholar 

  3. Ross WA et al. (2008) Combined EUS with FNA and ERCP for the evaluation of patients with obstructive jaundice from presumed pancreatic malignancy. Gastrointest Endosc 68: 461–466

    Article  Google Scholar 

  4. Christensen M et al. (2004) Complications of ERCP: a prospective study. Gastrointest Endosc 60: 721–731

    Article  Google Scholar 

  5. Mergener K et al. (1998) Pneumoperitoneum complicating ERCP performed immediately after EUS-guided fine needle aspiration. Gastrointest Endosc 47 541–542

    Article  CAS  Google Scholar 

  6. Di Matteo F et al. (2006) Same-day endoscopic retrograde cholangiopancreatography after transduodenal endoscopic ultrasound-guided needle aspiration: do we need to be cautious? Endoscopy 38: 1149–1151

    Article  CAS  Google Scholar 

  7. Tarantino I et al. (2007) Simultaneous endoscopic ultrasound fine needle aspiration and endoscopic retrograde cholangio-pancreatography: evaluation of safety. World J Gastroenterol 13: 3861–3863

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohamad A Eloubeidi.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Peter, S., Eloubeidi, M. Feasibility of combined EUS–FNA and ERCP for obstructive jaundice from presumed pancreatic malignancy. Nat Rev Gastroenterol Hepatol 6, 132–133 (2009). https://doi.org/10.1038/ncpgasthep1365

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpgasthep1365

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing