Parallel universes

Stephen B Hanauer

doi:10.1038/ncpgasthep0878 | Full Text | PDF (93K)

Disrupted sleep in patients with IBS—a wake-up call for further research?

Ami D Sperber and Ariel Tarasiuk

Disrupted sleep is reported by many patients with IBS, yet the role of sleep in IBS is not defined. This Viewpoint article discusses the subjective and objective evidence for disrupted sleep in patients with IBS, examines the relationship between gastrointestinal symptoms and sleep disturbance, and highlights areas for future research.

doi:10.1038/ncpgasthep0847 | Full Text | PDF (130K)

Tacrolimus is poorly tolerated by patients with primary sclerosing cholangitis

doi:10.1038/ncpgasthep0848 | Full Text | PDF (92K)

Technique for early prediction of local response to RT in patients with HCC

doi:10.1038/ncpgasthep0850 | Full Text | PDF (92K)

IBS associated with non-appendicitis appendectomy

doi:10.1038/ncpgasthep0851 | Full Text | PDF (101K)

Protease activity and visceral pain in IBS

doi:10.1038/ncpgasthep0852 | Full Text | PDF (90K)

Antiplatelet prophylaxis reduces the risk of HAT after liver transplantation

doi:10.1038/ncpgasthep0853 | Full Text | PDF (101K)

Sicca syndrome associated with chronic HCV infection and HLA genotype

doi:10.1038/ncpgasthep0854 | Full Text | PDF (91K)

The OLGA staging system for gastritis

doi:10.1038/ncpgasthep0855 | Full Text | PDF (91K)

Potential for oral oligofructose-enriched inulin in the treatment of ulcerative colitis

doi:10.1038/ncpgasthep0856 | Full Text | PDF (90K)

Perturbations in infant gut microbiota composition precede development of childhood atopy

doi:10.1038/ncpgasthep0857 | Full Text | PDF (90K)

Confocal endomicroscopy provides a virtual biopsy of the colon

doi:10.1038/ncpgasthep0858 | Full Text | PDF (101K)

Supplementation with vitamins E and C protects against ribavirin-induced hemolytic anemia

doi:10.1038/ncpgasthep0859 | Full Text | PDF (92K)

Fluoroscopic guidance not needed during bougienage for the treatment of Schatzki's rings

doi:10.1038/ncpgasthep0860 | Full Text | PDF (102K)

Aspirin does reduce the long-term risk of colorectal cancer

doi:10.1038/ncpgasthep0861 | Full Text | PDF (92K)

Pancreatic cancer and microRNA expression patterns

doi:10.1038/ncponc0903 | Full Text | PDF (92K)

Is there an increased risk of hip fracture in patients on long-term PPI therapy?

Nicholas J Talley, Hye Kyung Jung, Xuan Jiang and G Richard Locke

doi:10.1038/ncpgasthep0870 | Full Text | PDF (137K)

Is antifibrinolytic drug use in liver transplantation associated with an increased risk of thromboembolic events?

Andre De Wolf and Michael Abecassis

doi:10.1038/ncpgasthep0869 | Full Text | PDF (135K)

Tacrolimus or microemulsified ciclosporin for immunosuppression after liver transplantation?

Mubashir Khan, A Joseph Tector and Paul Y Kwo

doi:10.1038/ncpgasthep0874 | Full Text | PDF (138K)

Unsedated small-caliber endoscopy—a new screening and surveillance tool for Barrett's esophagus?

Matthew Atkinson and Amitabh Chak

doi:10.1038/ncpgasthep0880 | Full Text | PDF (140K)

Is the rate of adenoma detection in colonoscopy influenced by the duration of colonoscope withdrawal?

Paul D Collins and Alastair JM Watson

doi:10.1038/ncpgasthep0875 | Full Text | PDF (138K)

Probiotics for abdominal pain disorders in children—safe to use but are they helpful?

Miguel Saps and Carlo Di Lorenzo

doi:10.1038/ncpgasthep0842 | Full Text | PDF (139K)

Drug-induced injury in the gastrointestinal tract: clinical and pathologic considerations

Marc P Pusztaszeri, Robert M Genta and Byron L Cryer

Numerous drugs can damage the gastrointestinal tract, and improved recognition of drug-induced gastrointestinal tract pathology is needed to improve patient care. The authors of this Review discuss the most common and well-described drug-related clinicopathological conditions of the gastrointestinal tract. Much discussion is dedicated to NSAIDs—the most commonly prescribed drugs and consequently the drugs most commonly associated with gastrointestinal tract toxicity.

doi:10.1038/ncpgasthep0896 | Full Text | PDF (818K)

Mechanisms of Disease: chronic inflammation and cancer in the pancreas—a potential role for pancreatic stellate cells?

Hana Algül, Matthias Treiber, Marina Lesina and Roland M Schmid

Pancreatic stellate cells are the main mediator of fibrogenesis during chronic pancreatitis, and chronic pancreatitis is a consistent risk factor for pancreatic ductal adenocarcinoma. In this Review, the authors discuss the idea that pancreatic stellate cells have a linking role in the development of pancreatic ductal adenocarcinoma via their ability to communicate with inflammatory cells, acinar cells and pancreatic cancer cells.

doi:10.1038/ncpgasthep0881 | Full Text | PDF (424K)