"Hit me with your best shot...Fire away!"

Stephen B Hanauer MD

doi:10.1038/ncpgasthep0581 | Full Text | PDF (80K)

Should we incorporate psychological care into the management of IBS?

Olafur S Palsson

This Viewpoint discusses the limited effectiveness of standard medical treatments for IBS, which leave about half of patients without satisfactory symptom relief. The article argues that adjunctive psychological therapies might enhance overall IBS outcomes as evidence suggests that psychological treatments can provide long-lasting symptom improvement for the majority of patients with IBS that is refractory to medical treatment.

doi:10.1038/ncpgasthep0597 | Full Text | PDF (97K)

Delayed gastric emptying is unlikely to explain dyspeptic symptoms

doi:10.1038/ncpgasthep0562 | Full Text | PDF (104K)

Ileocolonoscopy outperforms WCE in postsurgical surveillance of Crohn's disease

doi:10.1038/ncpgasthep0563 | Full Text | PDF (92K)

Transgenic bacteria can be used to deliver IL-10 to gut mucosa

doi:10.1038/ncpgasthep0564 | Full Text | PDF (101K)

Endoscopic submucosal dissection in the treatment of esophageal neoplasms

doi:10.1038/ncpgasthep0565 | Full Text | PDF (104K)

GERD symptoms in women of normal weight

doi:10.1038/ncpgasthep0566 | Full Text | PDF (101K)

Some instances of cardiac dysrhythmia might be caused by GERD

doi:10.1038/ncpgasthep0567 | Full Text | PDF (104K)

Statins have potential in combination therapy for hepatitis C

doi:10.1038/ncpgasthep0568 | Full Text | PDF (92K)

Formalin instillation to treat hemorrhagic radiation proctopathy

doi:10.1038/ncpgasthep0569 | Full Text | PDF (91K)

Accurate upper gastrointestinal endoscopies can be performed by nurses

doi:10.1038/ncpgasthep0570 | Full Text | PDF (90K)

The influence of NSAID use on colorectal cancer risk

doi:10.1038/ncpgasthep0571 | Full Text | PDF (101K)

High serum resistin levels predict poor survival in patients with chronic liver disease

doi:10.1038/ncpgasthep0572 | Full Text | PDF (104K)

Monitoring gastric pH with the Bravo system

doi:10.1038/ncpgasthep0573 | Full Text | PDF (101K)

Fecal S100A12 is a promising noninvasive marker for pediatric IBD

doi:10.1038/ncpgasthep0574 | Full Text | PDF (104K)

STA5326 is a well-tolerated and effective treatment for active Crohn's disease

doi:10.1038/ncpgasthep0575 | Full Text | PDF (92K)

Helicobacter pylori infection relapse after eradication is not a problem in developed countries

Francis Mégraud and Herve Lamouliatte

doi:10.1038/ncpgasthep0600 | Full Text | PDF (105K)

How safe and useful are left-lobe grafts in living donor liver transplantation?

Abhinav Humar

doi:10.1038/ncpgasthep0598 | Full Text | PDF (101K)

What is the clinical importance of small polyps with regard to colorectal cancer screening?

Robert E Schoen and Chin Hur

doi:10.1038/ncpgasthep0599 | Full Text | PDF (102K)

How effective is itopride for the treatment of patients with functional dyspepsia?

Ahmed Madisch and Stephan Miehlke

doi:10.1038/ncpgasthep0579 | Full Text | PDF (100K)

Treatment of intestinal failure: home parenteral nutrition

Daniel K Mullady and Stephen JD O'Keefe

Home parenteral nutrition (HPN) has advanced since its introduction in the late 1960s, such that patients with intestinal failure can now survive and lead productive lives outside the hospital. This Review considers the indications for HPN, the complications that can arise, and the quality of life of patients on HPN.

doi:10.1038/ncpgasthep0580 | Full Text | PDF (448K)

Nonmalignant portal vein thrombosis in adults

Bertrand Condat and Dominique Valla

The authors of this Review focus on non-malignant portal vein thrombosis (PVT), the second most common cause of portal vein occlusion. Discussion includes how the two different forms of PVT—acute and chronic—are diagnosed, how they can be treated and what the outcomes are. PVT in the setting of cirrhosis and liver transplantation is also discussed.

doi:10.1038/ncpgasthep0577 | Full Text | PDF (456K)

Mechanisms of Disease: immunopathogenesis of celiac disease

Bana Jabri and Ludvig M Sollid

Celiac disease has previously been regarded as a benign intestinal disorder that can be easily treated by a gluten-free diet. This Review article discusses advances in the understanding of the genetics and immunology of celiac disease, and considers evidence for the independent existence of the adaptive and innate immune response to gluten.

doi:10.1038/ncpgasthep0582 | Full Text | PDF (283K)