Table of contents

August 2006 Volume 3 No 8

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Editorial

Safety first: messages from Digestive Disease Week 2006

Stephen B Hanauer

415

doi:10.1038/ncpgasthep0553 | Full Text | PDF (80K)


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Viewpoint

Should we incorporate psychological care into the management of IBD?

Gabriele Moser

416

The role of psychological distress in provoking and exacerbating IBD is controversial. This Viewpoint discusses the role of psychological factors in the pathogenesis of IBD and focuses on the need for including psychological care in the clinical management of patients with IBD.

doi:10.1038/ncpgasthep0549 | Full Text | PDF (96K)


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Research Highlights

Immunosuppressive therapy in adolescent liver transplant recipients

418

doi:10.1038/ncpgasthep0529 | Full Text | PDF (100K)

An NSAID plus a PPI reduces risk of dyspepsia in patients with arthritis

418

doi:10.1038/ncpgasthep0530 | Full Text | PDF (88K)

Serum resistin and leptin levels predict severity of acute pancreatitis

418

doi:10.1038/ncpgasthep0531 | Full Text | PDF (98K)

Promising results for multiple band ligation of prolapsed rectal mucosa

419

doi:10.1038/ncpgasthep0532 | Full Text | PDF (100K)

Antioxidants help relieve pain and improve quality of life for chronic pancreatitis patients

419

doi:10.1038/ncpgasthep0533 | Full Text | PDF (98K)

True upper normal limit of serum ALT is lower than usually claimed

420

doi:10.1038/ncpgasthep0534 | Full Text | PDF (101K)

Atorvastatin is safe and effective for dyslipidemic patients with NAFLD

420

doi:10.1038/ncpgasthep0536 | Full Text | PDF (99K)

Antifungal prophylaxis lowers risk of death after liver transplantation

421

doi:10.1038/ncpgasthep0535 | Full Text | PDF (102K)

Oat inclusion in the diet of children with celiac disease

421

doi:10.1038/ncpgasthep0537 | Full Text | PDF (90K)

A novel explanation for the role of dietary fiber in colorectal cancer

421

doi:10.1038/ncpgasthep0538 | Full Text | PDF (99K)

Open-access endoscopy has no impact on early detection of esophagogastric cancer

422

doi:10.1038/ncpgasthep0539 | Full Text | PDF (102K)

PPI-induced acute interstitial nephritis

422

doi:10.1038/ncpgasthep0540 | Full Text | PDF (99K)

Could MELD be improved by incorporating serum sodium level?

423

doi:10.1038/ncpgasthep0541 | Full Text | PDF (102K)

Genetic profiling could identify patients at risk of relapse of colorectal cancer

423

doi:10.1038/ncpgasthep0542 | Full Text | PDF (88K)


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Practice Points

Is it safe to raise the age threshold for urgent endoscopy in patients with uncomplicated dyspepsia?

Derek Gillen and Kenneth EL McColl

424

doi:10.1038/ncpgasthep0560 | Full Text | PDF (98K)

Serum hepatitis B virus DNA level as a risk predictor for liver disease complications

Frank Tacke and Christian Trautwein

426

doi:10.1038/ncpgasthep0561 | Full Text | PDF (101K)

Should PPIs be given to patients on antiplatelet drugs?

Stephan R Vavricka, Stephan M Wildi and Michael Fried

428

doi:10.1038/ncpgasthep0559 | Full Text | PDF (99K)

How effective are 3-month and 12-month predictive models of mortality after first liver transplantation?

Scott W Biggins

430

doi:10.1038/ncpgasthep0554 | Full Text | PDF (100K)

How useful is methylglucamine diatrizoate solution in patients with small-bowel obstruction?

Michael G Sarr

432

doi:10.1038/ncpgasthep0555 | Full Text | PDF (101K)

What is the clinical benefit of portal vein embolization before extended hepatectomy for biliary cancer?

Markus K Müller and Pierre-Alain Clavien

434

doi:10.1038/ncpgasthep0552 | Full Text | PDF (103K)


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Reviews

Treatment options for the eradication of intestinal protozoa

Michael JG Farthing

436

Pathogenic intestinal protozoa are responsible for clinically important infections in both the developed and developing world. Treatments have been available for several decades for giardiasis, isosporiasis and amoebiasis, but until recently there were no effective remedies for the intestinal coccidia—cyptosporidium, microsporidium and cyclospora. In this Review, the author discusses the various pathogenic intestinal protozoa and the treatment options available.

doi:10.1038/ncpgasthep0557 | Full Text | PDF (193K)

Treatment of chronic hepatitis B

Smruti R Mohanty, Sonia S Kupfer and Vijay Khiani

446

The treatment of chronic hepatitis B has improved substantially in recent years. FDA-approved therapies now include interferon alpha, pegylated interferon alpha2a, lamivudine, adefovir dipivoxil, and entecavir. Other antiviral agents and combination regimens are in various stages of development. This Review summarizes the results obtained for approved therapies and highlights emerging antiviral agents for the treatment of chronic hepatitis B.

doi:10.1038/ncpgasthep0550 | Full Text | PDF (256K)

Technology Insight: photodynamic therapy for cholangiocarcinoma

Maria-Anna Ortner and Gian Dorta

459

Cholangiocarcinoma is, in most cases, rapidly fatal, having an inadequate response to the treatment strategies currently available. The authors of this Review describe the mechanism of action, efficacy and complications of photodynamic therapy—a relatively new local, minimally invasive treatment for cholangiocarcinoma that uses the photo-physical properties of photosensitizers to destroy tumors.

doi:10.1038/ncpgasthep0543 | Full Text | PDF (320K)


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Case Study

Continuing Medical Education

A patient with abdominal pain and markedly elevated transaminase levels after cholecystectomy

Rajesh N Keswani, John Hart and Smruti R Mohanty

468

doi:10.1038/ncpgasthep0556 | Full Text | PDF (386K)


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