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Editorial

Nature Reviews Gastroenterology and Hepatology 3, 59 (1 February 2006) | doi:10.1038/ncpgasthep0411

The 'tipping point' applied

Stephen B Hanauer

The epiphany came while I was lecturing on the Positioning of biologic agents to treat inflammatory bowel disease at an annual Crohn's & Colitis Foundation of America conference. As I wrote in my November 2005 editorial, it can readily be debated that anti-tumor necrosis factor agents are the most efficacious treatment for IBD and can reduce side effects (compared with corticosteroids), hospitalizations and surgeries.