Table of contents
August 2005 Volume 2 No 8
Editorial
Viewpoint
Appendiceal function and dysfunction: what are the implications for inflammatory bowel disease?
338The ultimate function of the appendix still remains a mystery; however, increasing evidence suggests it has a role in many intestinal diseases. This viewpoint examines the controversy surrounding the role of the appendix in the etiology of inflammatory bowel disease.
Research Highlights
Free radical damage in gastroesophageal reflux disease
340Early perioperative management of bile duct injuries acquired during laparoscopic cholecystectomy
340Prophylactic anti-HBV therapy in hematopoietic stem-cell transplantation
340Multicenter findings on pediatric donor split-liver transplantation
341Colonoscopy versus sigmoidoscopy for colorectal cancer screening in average-risk women
341Call for modification of the esophageal cancer staging system
342Telomerase mRNA: a novel marker for hepatocellular carcinoma
343Frequent repetition of surgical technique needed for optimal results
343TRAIL receptors as a potential target for apoptosis induction in colorectal cancer
344Helicobacter pylori infection and gastric cancer: is there a role for eradication therapy?
344Practice Points
Can peptic ulcers be healed with 7 days of proton-pump-inhibitor-based triple therapy?
346Should azathioprine be withdrawn in patients with Crohn's disease who are in long-term remission?
348How does donor age influence the success of liver transplantation in patients with hepatitis?
350Should African Americans be screened for colorectal cancer at an earlier age?
352Reviews
Current management of locally advanced pancreatic cancer
356Almost 30% of patients with pancreatic cancer present with large, locally advanced tumors in the absence of distant metastases. Because surgical resection is often contraindicated by vascular invasion, this disease has a dismal prognosis. This Review summarizes the status of aggressive surgical resection and neoadjuvant chemoradiation for locally advanced pancreatic cancer and suggests a treatment algorithm based on published clinical evidence.
doi:10.1038/ncpgasthep0240 | Full Text | PDF (188K)

Technology Insight: enteral stenting and new technology
365The indications for self-expandable metallic stents (SEMS) now include relief of luminal obstruction of the upper gastrointestinal tract, colon or rectum, in which case they are referred to as enteral SEMS. The authors of this Review discuss data on the efficacy, complications, and cost effectiveness of enteral SEMS, and consider future directions for enteral stenting technology.
doi:10.1038/ncpgasthep0236 | Full Text | PDF (761K)


