Table of contents

August 2005 Volume 2 No 8

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Editorial

Novel potential perils of volunteering for clinical trials

Stephen B Hanauer

337

doi:10.1038/ncpgasthep0239 | Full Text | PDF (52K)


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Viewpoint

Appendiceal function and dysfunction: what are the implications for inflammatory bowel disease?

Karel Geboes

338

The ultimate function of the appendix still remains a mystery; however, increasing evidence suggests it has a role in many intestinal diseases. This viewpoint examines the controversy surrounding the role of the appendix in the etiology of inflammatory bowel disease.

doi:10.1038/ncpgasthep0238 | Full Text | PDF (71K)


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Research Highlights

Free radical damage in gastroesophageal reflux disease

340

doi:10.1038/ncpgasthep0223 | Full Text | PDF (57K)

Early perioperative management of bile duct injuries acquired during laparoscopic cholecystectomy

340

doi:10.1038/ncpgasthep0224 | Full Text | PDF (57K)

Prophylactic anti-HBV therapy in hematopoietic stem-cell transplantation

340

doi:10.1038/ncpgasthep0226 | Full Text | PDF (65K)

Multicenter findings on pediatric donor split-liver transplantation

341

doi:10.1038/ncpgasthep0227 | Full Text | PDF (58K)

Colonoscopy versus sigmoidoscopy for colorectal cancer screening in average-risk women

341

doi:10.1038/ncpgasthep0228 | Full Text | PDF (65K)

Diagnosis of the Lynch syndrome

342

doi:10.1038/ncpgasthep0229 | Full Text | PDF (57K)

Call for modification of the esophageal cancer staging system

342

doi:10.1038/ncpgasthep0230 | Full Text | PDF (64K)

Telomerase mRNA: a novel marker for hepatocellular carcinoma

343

doi:10.1038/ncpgasthep0231 | Full Text | PDF (57K)

Frequent repetition of surgical technique needed for optimal results

343

doi:10.1038/ncpgasthep0232 | Full Text | PDF (57K)

Obesity in GERD and erosive esophagitis

343

doi:10.1038/ncpgasthep0233 | Full Text | PDF (67K)

TRAIL receptors as a potential target for apoptosis induction in colorectal cancer

344

doi:10.1038/ncponc0239 | Full Text | PDF (60K)

Helicobacter pylori infection and gastric cancer: is there a role for eradication therapy?

344

doi:10.1038/ncponc0240 | Full Text | PDF (69K)

Prognostic factors affecting pancreatic adenocarcinoma

345

doi:10.1038/ncponc0242 | Full Text | PDF (60K)


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Practice Points

Can peptic ulcers be healed with 7 days of proton-pump-inhibitor-based triple therapy?

John C Atherton

346

doi:10.1038/ncpgasthep0235 | Full Text | PDF (76K)

Should azathioprine be withdrawn in patients with Crohn's disease who are in long-term remission?

Sandro Ardizzone and Gabriele Bianchi Porro

348

doi:10.1038/ncpgasthep0221 | Full Text | PDF (69K)

How does donor age influence the success of liver transplantation in patients with hepatitis?

Gero Puhl and Ulf Peter Neumann

350

doi:10.1038/ncpgasthep0234 | Full Text | PDF (74K)

Should African Americans be screened for colorectal cancer at an earlier age?

John M Carethers

352

doi:10.1038/ncpgasthep0241 | Full Text | PDF (75K)

Factors affecting therapeutic placebo response rates in patients with irritable bowel syndrome

Paul Enck, Sibylle Klosterhalfen and Wolfgang Kruis

354

doi:10.1038/ncpgasthep0237 | Full Text | PDF (73K)


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Reviews

Current management of locally advanced pancreatic cancer

Vivek Maheshwari and A James Moser

356

Almost 30% of patients with pancreatic cancer present with large, locally advanced tumors in the absence of distant metastases. Because surgical resection is often contraindicated by vascular invasion, this disease has a dismal prognosis. This Review summarizes the status of aggressive surgical resection and neoadjuvant chemoradiation for locally advanced pancreatic cancer and suggests a treatment algorithm based on published clinical evidence.

doi:10.1038/ncpgasthep0240 | Full Text | PDF (188K)

Continuing Medical Education

Technology Insight: enteral stenting and new technology

Dia T Simmons and Todd H Baron

365

The indications for self-expandable metallic stents (SEMS) now include relief of luminal obstruction of the upper gastrointestinal tract, colon or rectum, in which case they are referred to as enteral SEMS. The authors of this Review discuss data on the efficacy, complications, and cost effectiveness of enteral SEMS, and consider future directions for enteral stenting technology.

doi:10.1038/ncpgasthep0236 | Full Text | PDF (761K)


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