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Nature Reviews Gastroenterology and Hepatology 2, 338–339 (1 August 2005) | doi:10.1038/ncpgasthep0238

Appendiceal function and dysfunction: what are the implications for inflammatory bowel disease?

Karel Geboes

The ultimate function of the appendix still remains a mystery; however, increasing evidence suggests it has a role in many intestinal diseases. This viewpoint examines the controversy surrounding the role of the appendix in the etiology of inflammatory bowel disease.