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Nature Reviews Gastroenterology and Hepatology 2, 554 (1 December 2005) | doi:10.1038/ncpgasthep0324

Improved bone mineral density with alendronate in primary biliary cirrhosis patients

Katy Cherry

Zein CO et al. (2005) Alendronate improves bone mineral density in primary biliary cirrhosis: a randomized placebo-controlled trial. Hepatology 42: 762–771 Numerous studies have established a link between primary biliary cirrhosis (PBC) and loss of bone mass; however, a specific treatment regimen to improve bone mineral density (BMD) in such patients has yet to be established.