Early detection is the best opportunity to decrease cancer mortality rates. As such, a new study has made a head-to-head comparison of endoscopic ultrasonography and MRI for the detection of pancreatic lesions in high-risk asymptomatic individuals. Using multiple techniques for detection and screening could be the best approach.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Combined use of CEMIP and CA 19-9 enhances diagnostic accuracy for pancreatic cancer
Scientific Reports Open Access 21 February 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Rahib, L. et al. Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States. Cancer Res. 74, 2913–2921 (2014).
Lennon, A. M. et al. The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia? Cancer Res. 74, 3381–3389 (2014).
Siegel, R., Desantis, C. & Jemal, A. Colorectal cancer statistics, 2014. CA Cancer J. Clin. 64, 104–117 (2014).
Harinck, F. et al. A multicentre comparative prospective blinded analysis of EUS and MRI for screening of pancreatic cancer in high-risk individuals. Gut http://dx.doi.org/10.1136/gutjnl2014308008.
Shin, E. J. et al. Linear-array EUS improves detection of pancreatic lesions in high-risk individuals: a randomized tandem study. Gastrointest. Endosc. http://dx.doi.org/10.1016/j.gie.2015.02.028.
Tanaka, M. et al. International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas. Pancreatology 12, 183–197 (2012).
Canto, M. I. et al. Frequent Detection of Pancreatic Lesions in Asymptomatic High-Risk Individuals. Gastroenterology 142, 796–804 (2012).
Welch, H. G. & Passow, H. J. Quantifying the Benefits and Harms of Screening Mammography. JAMA Intern. Med. 174, 448–454 (2013).
Wu, J. et al. Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proc. Natl Acad. Sci. USA 108, 21188–21193 (2011).
Bettegowda, C. et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci. Transl. Med. 6, 224ra224 (2014).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
M.I.C. has collaborated with one of the authors of Harinck, F. et al.4
PowerPoint slides
Rights and permissions
About this article
Cite this article
Canto, M., Hruban, R. A step closer to screening for curable pancreatic cancer?. Nat Rev Gastroenterol Hepatol 12, 431–432 (2015). https://doi.org/10.1038/nrgastro.2015.112
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrgastro.2015.112
This article is cited by
-
Combined use of CEMIP and CA 19-9 enhances diagnostic accuracy for pancreatic cancer
Scientific Reports (2018)