The global burden of IBD: from 2015 to 2025

Journal name:
Nature Reviews Gastroenterology & Hepatology
Volume:
12,
Pages:
720–727
Year published:
DOI:
doi:10.1038/nrgastro.2015.150
Published online

Abstract

Over 1 million residents in the USA and 2.5 million in Europe are estimated to have IBD, with substantial costs for health care. These estimates do not factor in the 'real' price of IBD, which can impede career aspirations, instil social stigma and impair quality of life in patients. The majority of patients are diagnosed early in life and the incidence continues to rise; therefore, the effect of IBD on health-care systems will rise exponentially. Moreover, IBD has emerged in newly industrialized countries in Asia, South America and Middle East and has evolved into a global disease with rising prevalence in every continent. Understanding the worldwide epidemiological patterns of IBD will prepare us to manage the burden of IBD over time. The goal of this article is to establish the current epidemiology of IBD in the Western world, contrast it with the increase in IBD in newly industrialized countries and forecast the global effects of IBD in 2025.

At a glance

Figures

  1. Historical timelines of Crohn's disease and ulcerative colitis throughout the
                    world.
    Figure 1: Historical timelines of Crohn's disease and ulcerative colitis throughout the world.
  2. The global prevalence of IBD in 2015.
    Figure 2: The global prevalence of IBD in 2015.

    Data from Molodecky et al.4 Adapted from an image provided by PresenterMedia.

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Author information

Affiliations

  1. Departments of Medicine and Community Health Sciences, University of Calgary, 3280 Hospital Drive NW, 6D56 Calgary, AB, Canada T2N 4Z6.

    • Gilaad G. Kaplan

Competing interests statement

G.G.K. has previously served as a speaker for Abbvie, Jansen, Merck, Schering-Plough and UCB Pharma, and has previously participated in advisory board meetings for Abbvie, Jansen, Merck, Schering-Plough, Shire and UCB Pharma. G.G.K. has also received research support from Abbvie, GlaxoSmithKline, Merck and Shire.

Corresponding author

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Author details

  • Gilaad G. Kaplan

    Gilaad Kaplan is an Associate Professor in the Cumming School of Medicine at the University of Calgary, Canada. Dr Kaplan is a gastroenterologist and epidemiologist who has devoted his career to studying the environmental determinants of gastrointestinal diseases such as the inflammatory bowel diseases (IBD), and improving the care of patients living with these conditions. Dr Kaplan is an Alberta-Innovates Health-Solutions Population Health Investigator.

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