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GERD

Body position affects infant GER but not symptoms

Increased gastro-oesophageal reflux (GER) is described as a very common problem in infants. Loots et al. investigated the effect of the left lateral position on reflux and symptoms, finding that body position affects GER but not symptoms. The data highlight the difficulties faced in investigating reflux disease in the paediatric population.

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References

  1. Nelson, S. P., Chen, E. H., Syniar, G. M. & Christoffel, K. K. Prevalence of symptoms of gastroesophageal reflux during infancy. A pediatric practice-based survey. Pediatric Practice Research Group. Arch. Pediatr. Adolesc. Med. 151, 569–572 (1997).

    Article  CAS  Google Scholar 

  2. Dent, J., El-Serag, H. B., Wallander, M. A. & Johansson, S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 54, 710–717 (2005).

    Article  CAS  Google Scholar 

  3. van Wijk, M. P. et al. Effect of body position changes on postprandial gastroesophageal reflux and gastric emptying in the healthy premature neonate. J. Pediatr. 151, 585–590 (2007).

    Article  Google Scholar 

  4. Loots, C. et al. A randomized trial of body positioning and medical therapy for infantile gastroesophageal reflux symptoms. J. Pediatr. Gastroenterol. Nutr. http://dx.doi.org/10.1097/MPG.0000000000000395.

  5. Weusten, B. L., Roelofs, J. M., Akkermans, L. M., Van Berge-Henegouwen, G. P. & Smout, A. J. The symptom-association probability: an improved method for symptom analysis of 24-hour esophageal pH data. Gastroenterology 107, 1741–1745 (1994).

    Article  CAS  Google Scholar 

  6. Blair, P. S., Platt, M. W., Smith, I. J., Fleming, P. J. & the CESDI SUDI Research Group. Sudden infant death syndrome and sleeping position in pre-term and low birth weight infants: an opportunity for targeted intervention. Arch. Dis. Child. 91, 101–106 (2006).

    Article  CAS  Google Scholar 

  7. van der Pol, R. J. et al. Diagnostic accuracy of tests in pediatric gastroesophageal reflux disease. J. Pediatr. 162, 983–987 (2013).

    Article  Google Scholar 

  8. van der Pol, R. J. et al. Efficacy of proton-pump inhibitors in children with gastroesophageal reflux disease: a systematic review. Pediatrics 127, 925–935 (2011).

    Article  Google Scholar 

  9. Canani, R. B. et al. Therapy with gastric acidity inhibitors increases the risk of acute gastroenteritis and community-acquired pneumonia in children. Pediatrics 117, e817–e820 (2006).

    Article  Google Scholar 

  10. Hayat, J. O. et al. Pepsin in saliva for the diagnosis of gastro-oesophageal reflux disease. Gut http://dx.doi.org/10.1136/gutjnl-2014-307049.

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Correspondence to Daniel Sifrim.

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D.S. receives research grants from Reckitt Benckiser and Sandhill Scientific. P.W. declares no competing interests.

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Woodland, P., Sifrim, D. Body position affects infant GER but not symptoms. Nat Rev Gastroenterol Hepatol 11, 397–398 (2014). https://doi.org/10.1038/nrgastro.2014.92

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