A population-based study of all patients with primary biliary cirrhosis (PBC) diagnosed from 2000–2008 within a geographically defined area of the Netherlands has found that the incidence and prevalence rates of PBC increased over time (P <0.001). 992 patients with PBC were identified resulting in a mean incidence of 1.1 per 100,000 individuals; prevalence of PBC on 1 January 2008 was 13.2 per 100,000 individuals. PBC was not associated with smoking, age of menarche, age at first pregnancy or number of pregnancies.
References
Boonstra, K. et al. Rising incidence and prevalence of primary biliary cirrhosis: a large population-based study. Liver Int. 10.1111/liv.12434
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Incidence and prevalence of PBC is increasing. Nat Rev Gastroenterol Hepatol 11, 74 (2014). https://doi.org/10.1038/nrgastro.2014.3
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DOI: https://doi.org/10.1038/nrgastro.2014.3
