IBD has emerged as a global disease. Ng and colleagues have identified that some environmental risk factors are shared across the world, whereas others are distinctly unique to individuals living in Asia. This work adds a new clue to the mystery of the environmental determinates of IBD.
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References
Ng, S. C. et al. Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific. Gut http://dx.doi.org/10.1136/gutjnl-2014-307410.
Ng, S. C. et al. Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study. Gastroenterology 145, 158–165 (2013).
Molodecky, N. A. et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 142, 46–54 (2012).
Klement, E., Cohen, R. V., Boxman, J., Joseph, A. & Reif, S. Breastfeeding and risk of inflammatory bowel disease: a systematic review with meta-analysis. Am. J. Clin. Nutr. 80, 1342–1352 (2004).
Calkins, B. M. A meta-analysis of the role of smoking in inflammatory bowel disease. Dig. Dis. Sci. 34, 1841–1854 (1989).
Khalili, H. et al. Physical activity and risk of inflammatory bowel disease: prospective study from the Nurses' Health Study cohorts. BMJ 347, f6633 (2013).
Frolkis, A. et al. Environment and the inflammatory bowel diseases. Can. J. Gastroenterol. 27, e18–e24 (2013).
Ananthakrishnan, A. N. Environmental risk factors for inflammatory bowel diseases: a review. Dig. Dis. Sci. http://dx.doi.org/10.1007/s10620-014-3350-9.
Molodecky, N. A., Panaccione, R., Ghosh, S., Barkema, H. W. & Kaplan, G. G. Challenges associated with identifying the environmental determinants of the inflammatory bowel diseases. Inflamm. Bowel Dis. 17, 1792–1799 (2011).
Molodecky, N. A. & Kaplan, G. G. Environmental risk factors for inflammatory bowel disease. Gastroenterol. Hepatol. (NY) 6, 339–346 (2010).
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Kaplan, G. Global variations in environmental risk factors for IBD. Nat Rev Gastroenterol Hepatol 11, 708–709 (2014). https://doi.org/10.1038/nrgastro.2014.182
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DOI: https://doi.org/10.1038/nrgastro.2014.182
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