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Research Highlights
Nature Reviews Genetics 9, 570–571 (1 August 2008) | doi:10.1038/nrg2418
Small RNAs: Roundworm joins the piRNA club
Abstract
The Piwi subclass of Argonaute proteins associate with 24–30-nucleotide RNAs called Piwi-interacting RNAs (piRNAs) in the fruitfly, zebrafish, mouse and rat. Three new studies report the identification of a related class of 21-nucleotide RNAs, 21U-RNAs, as the piRNAs of Caenorhabditis elegans and suggest a function for Piwi and 21U-RNAs in the germ line.
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