Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Research Highlights
Nature Reviews Genetics 9, 326 (1 May 2008) | doi:10.1038/nrg2378
Epigenetics: Pioneering the path from methylation to transcription
Abstract
Epigenetic marks have a key role in setting up the transcriptional programmes that define specific cell types, but it is not clear how the marks are interpreted to give rise to differential transcription. New research shows that the FOXA1 transcription factor binds to methylated enhancers and opens the chromatin to facilitate access by other transcription factors.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
