Perspectives

Nature Reviews Genetics 9, 314-318 (April 2008) | doi:10.1038/nrg2316

EssayThe road to genome-wide association studies

Leonid Kruglyak1  About the author

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The recent crop of results from genome-wide association studies might seem like a sudden development. However, this blooming follows a long germination period during which the necessary concepts, resources and techniques were developed and assembled. Here, I look back at how the necessary pieces fell into place, focusing on the less well-chronicled days before the launch of the HapMap project, and speculate about future developments.

Author affiliations

  1. Leonid Kruglyak is at the Lewis-Sigler Institute for Integrative Genomics and the Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA.
    Email: leonid@genomics.princeton.edu

Published online 19 February 2008

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