Perspective

Nature Reviews Genetics 9, 231-238 (March 2008) | doi:10.1038/nrg2311

Article series: Historical Profiles

TimelineTheodor and Marcella Boveri: chromosomes and cytoplasm in heredity and development

Helga Satzinger1  About the author

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The chromosome theory of heredity, developed in 1902–1904, became one of the foundation stones of twentieth-century genetics. It is usually referred to as the Sutton–Boveri theory after Walter Sutton and Theodor Boveri. However, the contributions of Theodor Boveri and his co-worker, Marcella O'Grady Boveri (also his wife), to the understanding of heredity and development go beyond the localization of the Mendelian hereditary factors onto the chromosomes. They investigated the interaction of cytoplasm and chromosomes, and demonstrated its relevance in heredity and development.

Author affiliations

  1. Helga Satzinger is at the Wellcome Trust Centre for the History of Medicine, University College London, 183 Euston Road, London, NW1 2BE, UK.
    Email: h.satzinger@ucl.ac.uk

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