Review
Nature Reviews Genetics 7, 632-644 (August 2006) | doi:10.1038/nrg1901
Highly parallel genomic assays
Jian-Bing Fan1, Mark S. Chee2 & Kevin L. Gunderson1 About the authors
Abstract
Recent developments in highly parallel genome-wide assays are transforming the study of human health and disease. High-resolution whole-genome association studies of complex diseases are finally being undertaken after much hypothesizing about their merit for finding disease loci. The availability of inexpensive high-density SNP-genotyping arrays has made this feasible. Cancer biology will also be transformed by high-resolution genomic and epigenomic analysis. In the future, most cancers might be staged by high-resolution molecular profiling rather than by gross cytological analysis. Here, we describe the key developments that enable highly parallel genomic assays.
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Author affiliations
- Illumina Inc., 9885 Towne Centre Drive, San Diego, California 92121, USA.
- Prognosys Biosciences Inc., 505 Coast Boulevard, La Jolla, California 92037, USA.
Correspondence to: Kevin L. Gunderson1 Email: kgunderson@illumina.com
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