Perspectives

Nature Reviews Genetics 7, 482-488 (June 2006) | doi:10.1038/nrg1872

OpinionAddressing the problems with life-science databases for traditional uses and systems biology

Stephan Philippi1 & Jacob Köhler2  About the authors

Top

A prerequisite to systems biology is the integration of heterogeneous experimental data, which are stored in numerous life-science databases. However, a wide range of obstacles that relate to access, handling and integration impede the efficient use of the contents of these databases. Addressing these issues will not only be essential for progress in systems biology, it will also be crucial for sustaining the more traditional uses of life-science databases.

Author affiliations

  1. Stephan Philippi is at the Department of Computer Science, University of Koblenz, PO Box 201602, 56016 Koblenz, Germany.
  2. Jacob Köhler is at the Biomathematics and Bioinformatics Division, Rothamsted Research, Harpenden, Hertfordshire, AL5 2JQ, UK.

Correspondence to: Stephan Philippi1 Email: stephan.philippi@uni-koblenz.de

Published online 9 May 2006

MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated.

REVIEWS

Linking publication, gene and protein data

Nature Cell Biology Review (01 Nov 2006)

Integrating biological databases

Nature Reviews Genetics Review (01 May 2003)

e-Science: relieving bottlenecks in large-scale genome analyses

Nature Reviews Microbiology Perspective (01 Dec 2008)

See all 13 matches for Reviews

NEWS AND VIEWS

Standardizing the standards

Molecular Systems Biology News and Views (21 Feb 2006)

RESEARCH

Surrogate Endpoints for the Treatment of Venous Leg Ulcers

Journal of Investigative Dermatology Original Article

See all 9 matches for Research