Figures and Tables

From the following article:

Genetics of autoimmune diseases — disorders of immune homeostasis

Peter K. Gregersen & Timothy W. Behrens

Nature Reviews Genetics 7, 917-928 (December 2006)

doi:10.1038/nrg1944

Figure 1 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Figure 1

The innate and adaptive immune systems and the overlap between them.

Figure 2 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Figure 2

Central and peripheral tolerance mechanisms.

Figure 3 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Figure 3

Co-stimulatory and co-inhibitory molecules set thresholds for T-cell activation.

Figure 4 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Figure 4

Regulation of LCK tyrosine kinase activity by PTPN22 and CSK.

Figure 5 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Figure 5

Model of innate immune responses in autoimmunity.

Figure 6 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Figure 6

Activation of interferon production through TLR7 and TLR9 receptors.

Table 1 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Table 1

Sibling risk and HLA associations for selected autoimmune disorders

Table 2 - Genetics of autoimmune diseases |[mdash]| disorders of immune homeostasis

Table 2

Non-HLA susceptibility genes for autoimmune disease