Review

Nature Reviews Genetics 7, 873-884 (November 2006) | doi:10.1038/nrg1923

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Bridging the regeneration gap: genetic insights from diverse animal models

Alejandro Sánchez Alvarado1 & Panagiotis A. Tsonis2  About the authors

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Significant progress has recently been made in our understanding of animal regenerative biology, spurred on by the use of a wider range of model organisms and an increasing ability to use genetic tools in traditional models of regeneration. This progress has begun to delineate differences and similarities in the regenerative capabilities and mechanisms among diverse animal species, and to address some of the key questions about the molecular and cell biology of regeneration. Our expanding knowledge in these areas not only provides insights into animal biology in general, but also has important implications for regenerative medicine and stem-cell biology.

Author affiliations

  1. Howard Hughes Medical Institute, University of Utah School of Medicine, Deptartment of Neurobiology and Anatomy, Salt Lake City, Utah 84132, USA.
  2. Department of Biology and Center for Tissue Regeneration and Engineering, University of Dayton, Dayton, Ohio 45469, USA.

Correspondence to: Alejandro Sánchez Alvarado1 Email: sanchez@neuro.utah.edu

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