Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Review
Nature Reviews Genetics 5, 911–922 (1 December 2004) | doi:10.1038/nrg1491
The genetics of cell death: approaches, insights and opportunities in Drosophila
&
Abstract
Cell death is ubiquitous in metazoans and involves the action of an evolutionarily conserved process known as programmed cell death or apoptosis. In Drosophila melanogaster, it is now uniquely possible to screen for genes that determine the fate — life or death — of any cell or population of cells during development and in the adult. This review describes these genetic approaches and the key insights into cell-death mechanisms that have been obtained, as well as the outstanding questions that these techniques can help to answer.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
