Review
Nature Reviews Genetics 4, 110-118 (February 2003) | doi:10.1038/nrg995
Caenorhabditis elegans operons: form and function
Thomas Blumenthal1 & Kathy Seggerson Gleason1 About the authors
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Abstract
Nematodes are unusual among animals in having a substantial proportion of their genes arranged in polycistronic clusters that are similar to bacterial operons. Recently, a nearly complete database of the Caenorhabditis elegans genes that are transcribed in operons has been produced. Analysis of this database has identified the types of genes that are contained in the operons and the extent to which operons co-regulate genes of related function.
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Author affiliations
- Department of Biochemistry and Molecular Genetics, Box B-121, University of Colorado School of Medicine, Denver, Colorado 80262, USA.
Correspondence to: Thomas Blumenthal1 Email: tom.blumenthal@uchsc.edu